SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL COUMARIN DERIVATIVES AS ANTIOXIDANT AGENTS

© 2015 K. H. Randive, V. Jaishree^#, K. Santosh Patil, and Kumar Patil

^#E-mail: jaishreek2@rediffmail.com

Department of Pharmaceutical Chemistry, SAC College of Pharmacy, B.G. Nagara-571448, Karnataka, India

Received May 10, 2014; in final form, November 22, 2014

Coumarins have been isolated from plants and reported for antioxidant properties. In the present study, we report synthesis of new coumarin derivatives as prospective therapeutic agents and investigate their antioxidant properties.

Keywords: coumarin derivatives, antioxidant activity, free radical scavenging, reducing power, total antioxidant capacity.