8-Methoxy-5-quinolinesulphonyl chloride, a new fluorogenic reagent for detection of amines and amino acids

A. I. Tochilkin, I. N. Grachyova

Institute of Biological and Medical Chemistry, Academy of Medical Sciences of the USSR, Moscow

Abstract: A new fluorogenic reagent, 8-methoxy-5-quinolinesulphonyl chloride, was synthesized. It forms intensively fluorescing sulphonylamide derivatives of primary amines, amino acids and peptides, which can be analysed by thin-layer chromatography on the pmole level.

Russian Journal of Bioorganic Chemistry 1990, 16 (7):956-962

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