Submission of a Manuscript to the Editorial Board
1. The manuscript should be submitted as an electronic version to our e-mail: email@example.com.
2. The abstract (not less than 250 words), body of the article, list of references, tables, figure legends, schemes, figures should be submitted as a single file with consecutive page numbering (format Microsoft Office Word).
3. Please, use Times New Roman font – 12 pt, one and one-half line spacing, margins: left – 2.5, right – 1.5, top and bottom – 1.5 cm, no hyphenation of words, left side alignment, the paragraphs are introduced using the option “Format/Paragraph”.
4. Each illustration is submitted on a separate page after References. Files created in TIFF, JPEG or GIF formats are also presented separately.
5. Authors that plan to publish a review article should first submit to the Editorial Board a preliminary annotation (size of two pages) explaining motivation and relevance of the proposed subject, propose content and structure of the review, the expeeted volume of manuscript, the number of illustrations, the approximate number of references and time interval of their citing.
6. The details for preparation of text of review and Illustrations, please read on the “GUIDELINES FOR AUTHORS” at http://pleiades.online/en/journal/biochem/.
7. A Cover Letter signed by all the authors should be provided with the manuscript. The letter should include the statement that the submitted work has not been published previously and that it is not under consideration for publication in other journals.
8. Together with the manuscript, the authors should also submit the Agreement with the Publisher of the English Version. The Agreement signed by the Authors should contain the all the author’s names and their complete affiliations. This contact information is necessary to forward the royalty payments. The template of agreement can be downloaded from Model Author's Agreement Form (Word Document).
9. For detailed information on the manuscript preparation, please, see The Guidelines for Authors.
Guidelines for Authors, 2005
Download "Guidelines for Authors" in pdf (60 kb).
Subjects of publication
The Journal publishes original articles dedicated to the investigations of structure, structure--activity relationships, and synthesis of biologically important high-molecular mass compounds (proteins, nucleic acids, polysaccharides, and mixed biopolymers of any type). The Journal publications also deal with the investigation of the chemical background for the activity of highly organized cell components (e.g., cell membranes or molecular receptor complexes), intact cells and organs, and the problems of neuro- and immunochemistry, biotechnology, and fundamental principles for developing the diagnosticums for the most important infectious diseases.
Considerable in the Journal is also given to new achievements in the field of low molecular weight bioregulators. Investigations of the natural products (e.g., peptides, peptide and steroid hormones, lipids, vitamins, antibiotics, prostaglandins, alkaloids, and other chemical compounds from microorganisms, fungi, plants, and animals), their synthetic analogues, and synthetic biologically active compounds (e.g., drugs or pesticides) can be the subject for publication. Ecological problems, analysis of natural toxicants and xenobiotics as well as the problems of environment protection from their impact are also the subject for publication.
1. The principal form of publication is a paper, containing results of original experimental or theoretical investigations.
Submitted manuscript should represent the new data that have not been published before. Papers containing detailed experimental material previously published in the form of short communication or thesis are also acceptable. In this case the paper should include a reference to the previous communication.
The length of manuscript including Tables and References is strictly limited to 40 000 characters and 8 figures.
2. The Journal also publishes the reviews and minireviews devoted to the most important achievements in the field of bioorganic chemistry.
The length of review including Tables and References is strictly limited to 60 000 characters and 15 figures. The review exceeding these limits should be divided into several parts and can be published in two or more issues of the Journal. The maximal length of a minireview is 20 000 characters and 5 figures.
Authors wishing to publish a review should submit for preliminary evaluation its annotation, which states briefly the reason for the topicality of the proposed subject and contains preliminary data on the contents and structure of the review, its length, the number of illustrations and references.
3. Reports of unusual urgency, significance and interest are published in the rubric LETTERS TO THE EDITOR. Their length should be strictly limited to two typewritten pages and two figures.
4. The Editorial Board also practices issuing special numbers of the Journal devoted to the important dates in the history of bioorganic chemistry and physicochemical biology and to publication of the reports and communications of the most important international congresses, symposia, and conferences held in Russia. Decisions on such special issues are taken according to the preliminary applications submitted to the Editorial Board not later than 6 months before the proposed event.
5. Information on past congresses, symposia, conferences, etc., including the summary communications most interesting to the audience of the journal is published under the rubric CHRONICLE.
6. The most interesting publications in related journals are placed under the rubric SCIENCE NEWS.
7. Books, reviews, and other printed editions of interest to bioorganic chemists are discussed under the rubric BOOK REVIEWS.
8. The rubric USEFUL INFORMATION presents materials that are helpful to readers of the journal in their scientific activities.
9. Articles should be published in Russian with the exception of papers and symposium reports of foreign authors. These can be written and published in English. The other articles submitted in English are translated to Russian.
1. Two copies of the double-spaced typewritten manuscript should be submitted to the Editorial Board. All pages of an article should be numbered consecutively including the list of references. If several papers are submitted simultaneously, the authors should indicate the order of their publication.
2. The text of the article should also be submitted in electronic form (see paragraph 15 of this section).
3. Papers and LETTERS TO THE EDITORS should be arranged in the following way:
4. In order to bring the English version of the article as close to the original as possible and to facilitate the translator's work, the authors are requested to present the English list of specific terms, name reactions and reagents, names of biological objects, and trivial names of chemical compounds, preparations, and reagents used in the course of the investigation. Submission of the full English version of the article translated by the authors (taking into account all improvements and corrections inserted in the process of the preparation of the Russian version) is also possible upon agreement with the Editorial Board. If the quality of translation is satisfactory it will be published and paid for.
(1) Rubric (if necessary). |
(2) Title of the article
(3) List of authors by initials and surname. If the work was carried out at more than one institution, then the names of authors should be followed by superscript asterisks to affiliate them to the corresponding institutions. It is also necessary to indicate the author for correspondence by a footnote; additional requisites of the author (phone, fax, e-mail) are also desirable. The list of used abbreviations should be given in a footnote.
(4)The full names of institutions including the name of the city and the full mailing address where the author for correspondence works.
(5) The abstract (no more than 1.5 typewritten pages, i.e., ~2500 characters) with a brief description of the content and the most significant results of the work. The use of formulas in a graphic format is not recommended in the abstract. The abstract is a separate part of the manuscript, and therefore, all necessary abbreviations and conventional signs must be indicated here.|
(6) Key words (no more than 6 words).|
(7) A section entitled INTRODUCTION.|
(8) A section entitled RESULTS AND DISCUSSION|
(9) An EXPERIMENTAL section. This should include enough details to permit reproduction of the experiments and include the detailed characteristics of the reagents and sorbents used or the methods of their preparation, the instruments applied, references to the standard procedures, etc. |
(10) ACKNOWLEDGMENTS (if necessary). The names of funding organizations should be written out in full, and grant (project) numbers should be given. |
(11) REFERENCES (on separate sheets). |
(12) TABLES (each on a separate sheet with its own heading). |
(12) FIGURE AND SCHEME CAPTIONS. All figure captions should be typed together on one or more separate sheets. The same is applicable to the scheme captions. |
(13) Figures, schemes, and chemical formulas (each illustration on a separate sheet) |
(14) English version for items 2--6 (i.e., for the title, the list of authors by the initials and surname, the list of affiliations and addresses of the authors, the abstract, and key words).|
The author submitting an article to the Editorial Board should present the written evidence that its publication has been approved by all coauthors.
5. Tables, figures, and schemes should be numbered in the same order in which they are mentioned in the text, and their desired positions should be indicated by pencil in the margin of the article.
6. Figures and photographs should be carefully prepared and submitted in two copies. Each figure should be marked at the bottom of the front side with the name of the journal, the name of the first author, and the figure number. For optimal reproduction, the width and height of the original figure should be one and a half or twice the publication size. The photographs should be sharp, clear and printed on glossy white photographic paper. Electronic copies of complex figures and photographs are necessary (see paragraph 15 of the section). Curves on the figures should be designated with numbers (in italics). All the symbols and designations used in a figure should be cleared in the figure caption. For the figures reproduced from an original publication, a copy of a written permission for the publication should be presented by the article authors.
7. Chemical formulas and schemes should be either carefully written in the text or, like figures, typed together on separate sheets. Chemical formulas and compounds are numbered with bold Roman numerals enclosed in parentheses in the same order in which they are mentioned in formulas, schemes, or tables.
8. As a rule, figure captions and table legends should be comprehensible without reference to the text (unless this information has been already included in another caption, legend, or the Experimental section). Arrangement of the information in tabular or graphical form is not recommended if the same information can be presented more effectively by a mathematical expression or by running text.
9. References to the cited literature should be numbered with Arabic numerals enclosed in square brackets in the order of their citation in the text. If the article is part of a serial publication the previous communication should be numbered as  in the list of references. This reference is inserted in a footnote on the first page of the article. References cited in the tables or in the figure captions are numbered according to the position of the corresponding material in the text. REFERENCES should be listed after ACKNOWLEGMENTS in numerical order. For books translated into Russian, original issues must be cited first.
Reference to an article in press is possible only when it has been accepted for publication.
Literature references should be arranged and punctuated with all the authors indicated as shown:
All journals that are listed in the Chemical Abstracts Service Source Index should be abbreviated as they appear there. The names of Russian editions are presented according to VINITI recommendations in transliterated form.
1. Tikhonov, A.N. and Arsenin, V.Ya., Solution of Ill-Posed Problems, Winston, V.H., Ed., Washington: Harper and Brace, 1977.
Collection of Articles |
2. Knorre, D.G. and Lavrik, O.I., in: Theory and Practice in Affinity Techniques, Sundaram, P.V. and Eckstein, F., Eds., London: Academic, 1978, pp. 169?178.
3. Ulrich, D.R., J. Non-Cryst. Solids, 1988, vol. 100, no. 1?3, pp. 174?193.
4. Cheishvili, T.Sh., Study of Glasses of the Surface Phenomena in Marganese-Containing Glasses, Cand. Sci. (Chem.) Dissertation, Moscow: Research Inst., 1981, p. 45.
Patents and Inventor's Certificate |
5. Lyle, F.R., US Patent 5 973 257, Chem. Abstr., 1985, vol. 65, p. 2870.
6. Ivanov , S.A., USSR Inventor's Certificate no. 127, Byul. Izobr., 1983, no. 9, p. 195.
7. Ivanov, I.I., Pharmacology of Indole Derivatives, Available from VINITI, 1984, Moscow, no. 1831.
10. The Latin names of animals, plants, and microorganisms should be used. The genus and species should be given in italic and the higher taxons, in regular font. When cited first, the full genus name should be used.
11. Enzymes should be named according to IUB classification, followed by the current Enzyme Commission (EC) number in parentheses (see Appendix 4 ànd also www.chem.qmw.ac.uk/iubmb/enzyme/).
12. The amino acid sequences of proteins determined by their direct sequencing (rather than by the translation of nucleotide sequences) and their characteristics (such as subunit structure, functions, localization inside or outside the cell, etc.) should be submitted to SWISS-PROT at the European Institute of Bioinformatics (http://www.ebi.ac.uk), using e-mail: firstname.lastname@example.org or email@example.com; the received accession numbers should be placed into article.
13. The names of chemical compounds should be consistent with the nomenclature recommended by the International Union of Pure and Applied Chemistry (IUPAC) and International Union of Biochemistry (IUB) (see IUPAC's Nomenclature of Organic Chemistry, 3rd ed., IUPAC's Nomenclature of Inorganic Chemistry, 2nd ed.; see also Appendix 4 and http://www.acdlabs.com/iupac/nomenclature/93/r93_15.htm
14. Standard abbreviations and symbols recommended by IUPAC-IUB Commission on biochemical nomenclature should be used to designate the trivial names of chemical compounds and groups (residues, radicals, substituents) (see Appendices 1 and 2, the IUPAC-IUB rules are given in Appendix 4 and published in Eur. J. Biochem., 1983, vol. 131, no. 1, and the Web Sites: http://www.chem..qmw.ac.uk/iubmb/nomenclature and http://www.chem..qmw.ac.uk/iupac).
Nonstandard abbreviations of chemical compounds and general abbreviations are recommended only if complicated word combinations are repeatedly used in the text. When necessary, they should be composed in accordance with the international rules for the usage of chemical symbols; the application of ambiguous literal cryptograms is not recommended [e.g., Me4Si or Me3Si are preferable to TMS; (MeO)2Tr is better than DMTr, etc.].
The use of cryptograms for enzyme names (e.g., LDH for lactate dehydrogenase) is not recommended. Abbreviated names of enzymes consisting of the substrate symbol and the type of enzyme activity (D-Gln transferase, Hse dehydrogenase) are acceptable.
All nonstandard abbreviations as well as standard abbreviations included in IUPAC-IUB recommendation but not included in Appendices 1 and 2 should be defined in the footnote to the first sentence of the article.
The abbreviations given in Appendices 1 and 3 do not require decoding.
International System of Units (SI) should be used. Some supplementary units are also acceptable; e.g., A, cal, dpm, mm Hg, etc.
15. The electronic version of the article should be submitted on 3.5" MS-DOS formatted diskettes. The file should be prepared with Microsoft Word or Word for Windows. It is also desirable that the main text be presented in text format. Diskettes will be returned to the authors. The entire text of the article, including tables and figure captions, should be given as one file, named according to the name of the first author. To facilitate further operations with the files, one should use as few fonts as possible and format text as left aligned without word hyphenation. Carriage returns (Enter) should be used only to separate paragraphs, and special styles, templates, and macrocommands should be avoided.
Both scanned and computer-prepared black-and-white pictures are acceptable in electronic form. For half-tone photographs (drawings) and line-art-type drawings, the TIFF and JPEG formats are preferable. When preparing files in TIFF format, scanning should be performed with no less than 600 or 200 dpi resolution for half-tone photographs (drawings) and line-art-drawings, respectively. A separate file should correspond to each figure. For further explanations, see http://www.maik.ru.
The contents of the manuscript and the electronic version must be absolutely identical.
The accompanying letter should explain the content of all files, their formats, the coding for special symbols, etc.
Manuscript on acceptance
1. All articles submitted to the Editorial Board go through a two-step evaluation (the names of referees are not given to authors of papers they have refereed). Papers accepted for publication are thoroughly edited. Minor corrections to the style, nomenclature, and form are introduced in the article without author's consent. More significant improvements are to be agreed upon with the authors or the manuscript can be returned to the authors for revision to accommodate the remarks of the referees and the scientific editor. The authors should insert all the necessary corrections and clearly explain their position as to all the referee remarks in their reply to the Editorial Office. The manuscript should be returned as soon as possible together with the previous variant of the article and the diskette containing only the final variant. By mutual agreement with the Editorial Office, only an electronic final variant may be submitted.
The date of a paper's receipt is the date on which a version of the paper satisfying all the journal requirements is received. Revised articles returned to the Editorial Board after a time period of 2 or more months are registered as new ones with a new receipt date.
The priority of publication is established according to the receipt date. The works that the Editorial Board recognized as top-priority and significant, as well as the articles that require an urgent publication due to the causes that affect the author's interests are published ahead of line if the process of manuscript preparation would be not time-consuming.
2. After publication, 5 copies of the Russian version of the article along with an electronic variant of the English version are sent to the author.
3. The article can be declined by the Editorial Board for the following reasons:
4. In the case of a rejected article, the Editorial Office will send to the author a notice of rejection, one copy of the manuscript and the diskette.
(a) Incompatibility with the profile of the journal.|
(b) Insufficient significance of the results.
(c) Unclear formulation of the goals and objectives of the investigation.
(d) Failure to meet the current procedures and state of knowledge in the field.
(e) Insufficient substantiation of the conclusions in the literature and experimental material.
(f) The reported results have been previously published in detail by the authors of this article or by other researchers.
(g) Substandard quality the writing of the manuscript and/or failure to meet the requirements of Guidelines for Authors.
(h) The variant obtained by the Editorial Office after twofold rework had not took into account (without any comment) all the remarks of referee.
5. Mail (Shemyakin--Ovchinnikov Institute of Bioorganic Chemistry, room 509, building 34, ul. Miklukho-Maklaya 16/10, Moscow, 117997 Russia), phone [+7 (095) 330-7783], e-mail (firstname.lastname@example.org), or fax [+7 (095) 335-7103 directed to the Editorial Office of Bioorganicheskaya Khimiya] can be used to communicate with the Editorial Office of Bioorganicheskaya Khimiya. For e-mail communication, charset us-ASCII, iso-8859-1, CP1251 (Windows), or KOI8-R cyrillic coding may be used. Decoders MIME, BinHex, or Unicode and archivers PKZIP, ARJ, or RAR may be used when e-mailing attached files.
Standard symbols of selected monomeric units (residues) and substituents (groups or radicals) in biopolymers*
|Asp, D||aspartic acid|
|Asx, B||asparagine or aspartic acid|
|Bu, Bui, Bus, But||respectively n-, iso-, sec-, tert--butyl|
|Dns||Dansyl [i.e., 5-(dimethylamino)-1-naphthalenesulfonyl]|
|Glu, E||glutamic acid|
|Glx, Z||glutamine or glutamic acid|
|Guo, G2*||guanosine |
|Ino, I2*||inosine |
|Lys, Ê||lysine |
|Met, Ì||methionine |
|MeOTr and (MeO)2Tr||methoxytrityl and dimethoxytrityl respectively|
|Nuc, N2*||an unspecified nucleoside|
|ONSu or OSu||succimidooxy|
|Pro, P||proline |
|Puo, R||an unspecified purine nucleotide |
|Pyd, Y||an unspecified pyrimidine nucleotide|
|Suc< , -Suc-||succinyl|
|Thd, T2*||ribosylthymine (not thymidine, which is designated as dT or dThd)|
|Thr, T||threonine |
|Tos or Ts||tosyl (p(i.e., -toluenesulfonyl))|
|Trt or Tr||trityl ((i.e.,triphenylmethyl)|
|Urd, U2*||uridine |
|ψrd, ψ2*||pseudouridine (5-ribosyluracil)|
|Xaa||an unspecified amino acid |
*These symbols should be used only in formulas, structures, tables, and figures.|
2*A one-letter symbol should not be used for base designation.
3*Similarly for other deoxynucleosides and deoxysugars.
4*Similarly for other uronic acids.
5*Similarly for other 2-amino-2-deoxysaccharides and their N-acetyl derivatives.
Standard abbreviations for selected names
|BSA||bovine serum albumin|
|CoA (CoASH), CoASAc||coenzyme A and acetylcoenzyme A, respectively|
|DNA, cDNA||deoxyribonucleic acid and complementary DNA, respectively|
|IgA, IgG, etc||immunoglobulin A, G, etc.|
|Ð||phosphate residue incorporated into compound|
*Similarly for other nucleoside 5'-mono-, nucleoside 5'-di-, and nucleoside 5'-triphosphates. |
Abbreviations for frequently encountered words and terms
|aa* ||amino acid residue (number)|
|EIA and ELISA||enzyme immunoassay and enzyme-linked immunosorbent assay, respectively|
|ESR||electronic spin resonance|
|GC or GLC||gas chromatography or gas-liquid chromatography, respectively|
|HPLC||high-performance liquid chromatography|
|J ||spin-spin coupling constant|
|m-, o, and p-||meta, ortho, and para|
|N*||normal concentration (of solution)|
|NMR||nuclear magnetic resonance|
|ORD||optical rotatory dispersion|
|OU or AU**||optical (or absorbance) unit|
|PAGE||polyacrylamide gel electrophoresis|
|PCR||polymerase chain reaction|
|U*||unit of enzyme activity|
|X-ray||X-ray diffraction structural analysis|
*With a numeral.|
List of recommendations of the IUPAC–IUB commission on chemical nomenclature (also see http://www.chem.qmul.ac.uk/iupac/)
|Natural products and related compounds ||Pure and Appl. Chem. 1999.V. 71. P. 587-643; |
Ibid. 2004. V.76. P. 1283-1292
|Stereochemistry||Ibid. 1996. V. 68. P. 2193-2222|
|NMR spectroscopy||Eur.J. Biochem. 1998. V. 256. P. 1-15|
|Mass spectrometry||Organ. Mass. Spectrom. 1979. V. 14. P. 1-2|
|Biochemical thermodynamics||Eur.J. Biochem. 1996. V.240. P. 1-14|
|Isotopically modified compounds||Ibid. 1978. V. 86. Ð. 9-25|
|Amino acids, peptides and their derivatives:|
| - nomenclature, abbreviations, and symbols||Ibid. 1984. V. 138. Ð. 9-37|
| - conformation||Ibid. 1969 V. 17. Ð. 193-201|
|peptide hormones||Ibid. 1975. V. 55. Ð. 485-486|
|Nucleotides and nucleic acids|
| - - abbreviations and symbols||
||Ibid. 1972. V. 25. Ð. 1|
| - - incompletely specific bases||Ibid. 1985. V. 150. Ð. 1-5|
| - conformation||Ibid. 1983. V. 131. Ð. 9-15|
|Lipids||Ibid 1977. V. 79. Ð. 11-12|
|Glycolipids||Ibid.1998. V. 257. P. 293-298|
|Steroids||Ibid. 1989. V. 186. Ð. 427-456|
|Phosphorus-containing compounds||Ibid. 1977. V. 79. Ð. 1-9|
|Carbohydrates, glycoproteins, and peptidoglycans: nomenclature, abbreviations, and symbols|
| - nomenclature, abbreviations, and symbols|| Carbohydr. Res. 1997. V. 297. P. 43-177|
| - Conformation of monosaccharides||Eur. J. Biochem. 1980. V. 111. P. 295-298|
| - Conformation of oligosaccharides||Ibid. 1983. V. 131. Ð. 5-7|
|Quinones with isoprenoid side chain||Ibid. 1975. V. 53. Ð. 15-18|
|Carotenoids||Ibid. 1972. V. 25. Ð. 397-408; 1975.V. 57. Ð. 1-7|
|Retinoids||Ibid. 1982. V. 29. Ð.1-5|
|Tocopherols and related compounds||Ibid. 1982.V.123.P. 473-475|
|Tetrapyrrols||Ibid. 1988. V. 178. P. 277-328|
|Corrinoids||Ibid. 1974. V. 45. Ð. 7-12|
|Prenols||Ibid. 1987. V. 167. Ð. 181-184|
|Vitamin B-6 and related compounds||Ibid. 1973. V. 40. Ð. 325-327|
|Vitamin D||Ibid. 1982. V. 124.Ð. 223-227|
|Enzymes: Nomenclature. Recommendations (1992)||San Diego: Acad. Press, 1992|
|Supplement 1||Eur. J. Biochem. 1994. V. 223. P. 1-5|
|Supplement 2||Ibid. 1995. V. 23|
|Supplement 3||Ibid. 1996. V. 237. P. 1-5|
|Supplement 4||Ibid. 1997. V. 250. P. 1-6|
|Supplement 5||Ibid. 1999. V.264. P.610-650|
|Supplement 6-9||Nomenclature Committee of the International Union of Biochemistry and Molecular Biology |
Symbols for selected physical and chemical values and units
|Symbol||Value||Unit of measure
|m||mass||kg, g, mg, μg, etc. (not m)
|Ì||molecular mass||Da* (Dalton)
|Ìr||relative molecular mass||dimensionless
|n||amount of substance|| mol, mmol, mmol, nmol, pmol, etc.
|ñB, [Â]||Concentration of substance B||M (mol/l), mmol, etc.
|s||Sedimentation coefficient||S (Svedberg, 10-13 s)
|T||thermodynamic temperature||K** (Kelvin)
|Å||energy||J or cal (4.1868 J)
|Ð||pressure||Pa (Pascal), bar (105 Pa), atm (101 325 Pa), or mmHg (1 torr, equal to 133.2 Pa)
|I||ionic strength||M, mM, etc.
|I||luminous intensity||cd (Candela)
|À||absorbance*** (–logI/I0) (-lg I/Io)||dimensionless
|e||molar absorption coefficient****||Ì-1 cm-1
|Le ||radioactivity (irradiation ability)||Bq (Becquerel, s-1) ) or Ci (Curie, 37 GBq)
|Chemical and enzymic reactions
|t||time||s (not sec), min (not mn), h (not hr)
|V||volume||dm3 (l), cm3 (ml),ml, nl, etc.
|Êm||Michaelis constant||M, mM, etc.
|Ês||substrate constant||M, mM, etc.
|Êi||inhibition constant||M, mM, etc.
|k||rate constant||s-1 or Ì-1 s-1
|V (or Vmax)||maximum value of reaction rate||M s-1 ñ-1
|H||Hill coefficient|| dimensionless |
|* One-twelfth of the mass of the nuclide 12Ñ. |
2* Not oÊ.
3* The term "optical density" should not be used.
4* The term "extinction" should not be used.